姓    名：王燕                                        

专业方向：药物分析

办公电话：0872-2257401

电子邮件：jessica9428@sina.com

通讯地址：云南省大理州大理市下关镇万花路22号大理大学下关校区

简历：王燕，博士，教授，博士生导师，云南省“兴滇英才”教学名师，主要从事药物代谢动力学、体内药物分析教学和科研工作，沈阳药科大学药物分析博士，中国药科大学药物分析博士后。主持国家自然科学基金1项和省级科研基金2项，主持云南省研究生导师团队建设项目1项，主持国家级教改项目1项和省级教改项目、课程建设项目共5项，以第一作者或通讯作者发表SCI 20余篇。现任中国药理学会药物代谢专业委员会青年委员。

研究领域：药物代谢动力学、民族药药效靶标和作用机制等研究

代表论著（限10篇）：

1、Yilin Wang, Yingxiang Wu, Xi Liu, Zhiyan Lu,Tianqian Li, Yang Jin, Yan Wang* and Jiali Zhu. Deciphering theimmunomodulatory mechanismsof Periplaneta americana extract CII-3: insight from integrated metabolomics and
network pharmacology,Frontiers in Cell and Developmental Biology, 2026, 13:1718560（中科院二区，IF:4.3）   

2、Jiayue Zhou, Yingxiang Wu, Zhiyan Lu,Yan Wang*. Integrating Network Pharmacology and Metabolomics to Reveal the Immunomodulatory Mechanism of Ethnomedicine Rodgersia sambucifolia Hemsl, Drug Design, Development and Therapy, 2024, 18, 4749-4778.（中科院二区，IF:4.8）

3、Zhimin Miao, Yong Lai, Yingying Zhao , Lingmin Chen, Jianeng Zhou, Chunyan Li and Yan Wang*.Protective Property of Scutellarin Against Liver Injury Induced by CarbonTetrachloride in Mices, Frontiers in Pharmacology, 2021, 12:710692.（中科院二区，IF:5.8）

4、Ling Tang, KeLi Wang, Chun Peng, XuanWei Li, Le Li, Yan Wang*, and Li Ding. A simplified and sensitive LC-APCI-MS/MS method for the quantification of propofol: Application to a bioequivalence study in healthy Chinese subjects, International Journal of Clinical Pharmacology and Therapeutics, 2020, 11, 664-674.

5、Chun Peng, Ling Tang, Keli Wang, Yan Wang*, and Li Ding. A novel LC-MS/MS method for the quantiffcation of ulipristal acetate in human plasma: Application to a pharmacokinetic study in healthy Chinese female subjects, International Journal of Clinical Pharmacology and Therapeutics, 2020, 11, 642-651.

6、Chun Peng, Shunbo Zhao, Ling Tang, Keli Wang ,Yan Wang*, Li Ding*.A simplified and reliable LC-tandem mass spectrometry method for determination of ulipristal acetate in human plasma and its application to a pharmacokinetic study in healthy Chinese volunteers, Biomedical Chromatography, 2020, e4908.

7、Yan Wang, Jin Lu, Tengfei Li, Shunbo Zhao, Wen Yang, Lingye Liu, Xing Shi, Li Ding. Investigation of a potential drug-drug interaction between salbutamol and ambroxol and bioequivalence of a new fxed-dose combination containing these two drugs in healthy Chinese subjects, International Journal of Clinical Pharmacology and Therapeutics, 2018, 56, 247-254.

8、Yan Wang, Jin Lu, Tengfei Li, Shunbo Zhao, Wen Yang, Lingye Liu, Xing Shi, Mtalimanja Michael, Li Ding. Pharmacokinetics and safety of salbutamol/ambroxol fxed-dose combination granules in healthy Chinese subjects, International Journal of Clinical Pharmacology and Therapeutics, 2018, 56, 597-603.

9、Yan Wang, Lanting Zhao, Tengfei Li, WenYang, Qian Li, Luning Sun, Li Ding. Pharmacokinetics and tissue distribution study of clevidipine and its primary metabolite H152/81 in rats, Biomedical Chromatography, 2017, 32(2), 1-11.

10、Yan Wang, Guo-Xiang Sun, Yang Jin, Xiu-man Xie, Yingchun Liu, Di-Di Ma,Jia-Yue Gao, Yan-Fei Li. Combinative method using multi-wavelength quantitative fingerprints and the DPPH radical-scavenging assay for holistic evaluation of San-Huang Tablet, Chinese journal of natural medicines, 2017, 15(4), 310-320.

承担科研项目情况（限5项）：

1、云南省科技厅项目（202101BA070001-217）：基于代谢组学、多肽组学和血清药物化学探讨美洲大蠊提取物CⅡ-3 增强机体免疫功能的物质基础和作用机制，2022/12-2025/11，主持，在研；

2、云南省昆虫生物医药研发重点实验室开放项目（AS2022001）：基于代谢组学和蛋白质组学的美洲大蠊活性提取物CⅡ-3免疫调控的药效作用靶点及其机制研究，2023/12-2024/11，主持，已结题；

3、国家自然科学基金项目（81560695）：多基源民族药岩陀DNA条形码识别系统构建，2016/1-2019/12，主持，已结题；

4、大理大学博士科研启动基金项目（KYBS201512）：传统中药现代质量控制方法技术研究，主持，已结题；

5、国家自然科学基金地区项目（81260512）：天然药物紫地榆防龋药理作用机制的药效学研究，主要参与，已结题；